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In summary, the combination of semaglutide and metformin offers a robust approach to managing type 2 diabetes and facilitating weight loss

If trials continue to go well, experts estimate: FDA submission: 2026 Possible approval: late 20262027 Thats best-case, not guaranteed

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It includes several recommendations suggesting clinicians use multi-component brief therapies and three single-component therapies: stimulus control, sleep restriction therapy, and relaxation therapy

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Diarrhea is one of the most frequently reported side effects of semaglutide, a GLP-1 receptor agonist used to treat type 2 diabetes and support chronic weight management