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Medications like semaglutide and orlistat are most effective when paired with a healthy diet and regular exercise

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The thigh is preferred by many because its consistent fat thickness supports predictable absorption, but rotation across all three sites is acceptable and may improve long-term tolerability

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The SURMOUNT trials showed tirzepatide at 15 mg achieving 15% to 21% weight loss by week 72, compared to semaglutide at 2.4 mg achieving approximately 15% by week 68

Combining genetic predisposition data with clinical evidence, provider expertise, and individual health history creates a more informed foundation for semaglutide treatment