semaglutide makes me tired Fatigue: Feeling Weak on Semaglutide Why Semaglutide Makes You Tired

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Moreover, the faster metabolic rate of short-acting GLP-1RAs may induce abrupt changes in gastrointestinal function, further supporting the higher incidence of nausea and vomiting with these agents

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Nevertheless, despite these side effects, many people find the injections to be an effective way to lose weight

1997 Nov;16(6):547-53

One reason for this is that semaglutide slows gastric emptying, meaning food stays in the stomach longer before moving into the small intestine