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In vivo electrophysiological recording During the experiment, the mice were first anesthetized with 4% isoflurane (i.r) in the chamber

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(4) in males, spontaneous erections are a pharmacological consequence of MC4R agonism and erections lasting more than four hours require emergency care

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For urinary tract infections (UTIs) , safe alternatives include: Nitrofurantoin (if eGFR 45 mL/min/1.73 m): 100 mg modified-release twice daily for 3 days for uncomplicated lower UTI in non-pregnant women