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adults were taking GLP-1 drugs for weight loss in late 2025, more than double the 5.8% reported in February 2024

It was easy to find that the results from the discovery cohort showed evidence of a significant association (OR = 0.24, 95%CI: 0.080.74, P = 0.013), whereas the results from the validation cohort, although suggestive of an association between GLP-1R expression and a low risk of developing DR, were not statistically relevant (OR = 0.61, 95%CI: 0.321.21, P = 0.161), a result that could be attributed to underlying differences in individual samples

many clinicians are exploring lower maintenance doses or intermittent strategies

But as for high doses of vitamin E, obtained from the Internet or local stores, it is a different story

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