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They found that BMSC-FNDC5-Exos inhibited the YAP/EGR1/ACSL4 axis, a key ferroptosis regulator

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As further consideration of translation of this therapeutic to the clinic, cochlear synaptopathy is implicated as a potential contributor to human tinnitus, although the published evidence is emerging and, so far, is largely indirect 11,60

Additionally, hUC-MSCs have been found to improve ovarian function and endometrial tolerance in POF mice by modulating the T helper cell type 1/ T helper cell type 2 (Th1/Th2) cytokine balance, decreasing levels of Th1 cytokines (such as IFN- and IL-2), and significantly increasing the levels of the Th2 cytokine IL-4

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