This mechanism is what separates peptides Ipamorelin from synthetic Human Growth Hormone injections, which bypass the pituitary gland entirely
Rosario LA, O'Brien ML, Henderson CJ, Wolf CR and Tew KD
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An EC alternative was explored by Pei et al
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Hani U, Osmani RA, Siddiqua A, Wahab S, Batool S, Ather H, Sheraba N, Alqahtani A (2021) A systematic study of novel drug delivery mechanisms and treatment strategies for pancreatic cancer