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Humane endpoints were prospectively defined prior to study initiation and included sustained anorexia, marked body weight loss, persistent gastrointestinal disturbances, or other signs of clinical deterioration compromising animal welfare

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It seems that semaglutide used for weight loss among patients with obesity does not meet typical cost-effectiveness standards

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Additionally, for diabetic patients, the difficulty in managing blood sugar levels can lead to acute complications such as diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS), both of which can be fatal if not promptly treated

She has stated that she has no financial interests related to this article