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In accordance with this regulatory mechanism, which may be physiologically significant, homocysteine metabolism is challenged toward the production of cysteine and glutathione through the transsulfuration pathway in human liver cells exposed to oxidative conditions (Mosharov et al, 2000)

As this is a peptide-based drug, it becomes harder to replicate than small-molecule generics

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However, recent study shows that there is a synergistic effect of GIP and GLP-1 co-agonists in weight lowering (100) and glycemic improvement in patients with type 2 diabetes than mono-agonist (101)

Redox Biol (2016) 8:37582.10.1016/j.redox.2016.03.005 13 WeberGFSwirskiFK

They mimic the action of endogenous glucagon-like peptide 1, a hormone involved in glucose regulation and appetite control