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In trials of the branded formulations, STEP 1 reported a -14.9% mean body-weight change with semaglutide at 68 weeks, and SURMOUNT-1 reported -20.9% with 15 mg tirzepatide at 72 weeks

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Wipe the vial stopper with an alcohol swab before inserting the needle

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Individuals with a homozygous A allele of the CYP1A2 gene tend to produce more cytochrome P450, an enzyme responsible for about 95% of caffeine metabolism, and consequently metabolize CAF more quickly