Any references to tissues, cells, or pathways are provided for research context only and do not imply therapeutic or clinical use
Given the limited number of human clinical trials (only three published), the full side effect profile may not be completely characterized
Finally, we tested the impact of chemical inhibition of glutathione reductase and thioredoxin reductase using 1,3-bis-(2-chlorethyl)-l-nitroso-urea (BCNU) and auranofin, respectively ( Figure 7 HJ )
While that might not sound glamorous, its actually a stroke of biological geniusbecause the stomach is one of the most hostile environments in the body, constantly exposed to acids, bacteria, and inflammatory triggers
While early results are promising, many studies are either small, in-vitro, or not rigorously controlled
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