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Peptide treatment should not be presented as a guaranteed way to build muscle or replace evidence-based exercise and nutrition

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Metformin , the first-line type 2 diabetes drug and an AMPK activator, has cognitive data that are observational and inconsistent, and it lowers BDNF, a growth factor the brain relies on and that exercise raises, which is a reason for caution in a healthy brain

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The effect of metformin and standard therapy versus standard therapy alone in nondiabetic patients with insulin resistance and nonalcoholic steatohepatitis (NASH): A pilot trial