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The complete selection process, including the number of records identified, screened, and excluded with explicit reasons (separated for preclinical and clinical/epidemiological literature), is documented in the PRISMA flow diagram (Figure 1)

Semaglutide has more long-term safety data and is often more affordable

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There have been many placebo-controlled trials that have tracked symptoms, and this data has been reliably captured, says Pinto

UK consensus and NICE resources emphasise these mechanisms and management approaches

It is a drug that we anticipate will require long-term use, Hurtado Andrade adds