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Larger, well-controlled studies are essential to confirm efficacy and guide personalized strategies

Detailed examination of a subset of these patients indicates that these metabolic abnormalities are at least partly due to TCAC and ETC dysfunction

A.SierraJ

10,3 e0122124

Preclinical studies with a long-acting polyethylene glycosylated (PEGylated) FGF21 analog, B1344, in non-human primates with non-alcoholic liver disease demonstrated reduction of steatosis, attenuation of inflammation and fibrosis, and reduced hepatocyte injury after 11 weeks of therapy as assessed by analyzing liver biopsies [36]

Using MetaboAnalyst 4.0 for Comprehensive and Integrative Metabolomics Data Analysis