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Animal studies on retatrutide and liraglutide suggest a potential increase in thyroid cancer risk, although there is no evidence to indicate this risk extends to humans

This is because overseas manufacturers and suppliers operate outside Australian jurisdiction, and therefore cannot be compelled to comply with the Therapeutic Goods Act 1989 (Cth) or any other Australian therapeutic goods legislation. New regulations in New Zealand In May 2026, the New Zealand Medicines and Medical Devices Safety Authority (Medsafe) issued a formal consumer advisory warning New Zealanders against purchasing or using unapproved synthetic peptides and Selective Androgen Receptor Modulators (SARMs) promoted online

Exendin-4 also could ameliorate brain levels of APP and A, elevated by STZ-induced diabetes, in 3Tg-AD mice (151)

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