It is mainly expressed in adipocytes and hepatocytes, but it might also be detected in cardiomyocytes and skeletal muscle myocytes (46, 47)
Table 1: Total GLP-1-drug sales (US, $m) Ive crunched the numbers and I think there is a big opportunity here for the obesity market but perhaps not as big as people think
Although no medication is specifically approved to treat IR, we summarized the lifestyle changes and pharmacological medications that have been used as efficient intervention to improve insulin sensitivity
120 / 2019 / 2024
Burke LE, Wang J, Sevick MA
The strongest candidates are patients with documented poor sleep quality (especially inadequate slow-wave sleep), elevated or dysregulated cortisol, and co-existing metabolic markers such as insulin resistance, rising fasting glucose, low IGF-1, or visceral fat accumulation