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A 2024 JAMA analysis found no added benefits to combining these medications, only heightened health risks such as hypoglycemia or dehydration from compounded gastrointestinal strain

And the modified amino acids at positions 2 and 13 provide some protection against salivary enzymes, though these enzymes are less aggressive than gastric and intestinal proteases

[1] [3] Understanding these potential effects helps ensure safe and effective concurrent therapy

If your first option isnt covered, another GLP-1 might be

Filed Under: clinical trials, Drug Discovery, Metabolic disease/endicrinology