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The role of ferroptosis in acute kidney injury

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The second affects the cystathionine-beta-synthase (CBS) enzyme responsible for removing excess sulfur-containing amino acids from the system and converting homocysteine into cystathionine

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This effect of AMPK signaling is in agreement with our previous studies showing that, despite having 15% and 40% of WT total and mitochondrial GSH levels (respectively), livers from nave GCLM KO mice maintain structural and functional integrity of the mitochondria and show induction of ER stress-related genes 17,38