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Understanding the underlying mechanisms and triggers of hyperpigmentation is essential for selecting appropriate treatment approaches that address the root cause rather than merely masking symptoms

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Most covered patients pay less than $100/month: Among those with coverage for weight loss, about two-thirds have copays of $100 or less per month, and 40% pay $50 or less

Notably, the STEP (Semaglutide Treatment Effect in People with obesity) trials, which specifically examined body composition, demonstrated substantial weight loss compared with placebo (NCT03548935) [53], and reductions in fat mass and visceral adipose tissue were accompanied by decreases in lean mass, although the proportion of lean mass relative to total body mass increased (NCT04074161) [54]

Protocols, timelines, side effects, and results covered in full