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Outcome findings from NMA Using a Bayesian network meta-analysis to simultaneously examine the differences in each treatment for each outcome measure, the study found that no specific treatment showed statistically significant improvement compared to the control group in all outcomes (pain, frequency, urgency, nocturia, ICPI, ICSI, PUF and FBV) (Fig

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Modulation of gamma-aminobutyric acid (GABA)related signaling has been observed in preclinical models, a mechanism that may contribute to reduced anxiety-like behaviors and enhanced neural stability (27)

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