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The safety issues are still the unknown, versus so far the safety looks to be good, right

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This could include chronic non-healing wounds, specific types of musculoskeletal injuries, or certain gastrointestinal disorders

- GRAS Approved: Recognized by the US FDA as Generally Recognized as Safe. - Significant Benefits over NSAIDs: In animal studies, CelaCor was as effective as repeated doses of naproxen or ibuprofen in suppressing polyarthritis and three times more efficacious than aspirin

Moreover, Beclin-1 also suppresses the NTase activity of cGAS to decrease the production of the secondary messenger cGAMP and type I IFN production (150, 154)