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Mechanistically, confirming the bioinformatic prediction, palmatine downregulated the expression of the five key targets and concurrently suppressed the activation of critical apoptotic executers (Caspase-3, Caspase-8, GSDME)
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doi: 10.1210/jcem-40-5-764 527 FarazAWaheedANazirMMHameedATauqirNAMirzaRHet al
KEGG analysis of these differentially regulated proteins (133 decreased and 43 increased) enriched pathways related to focal adhesion, T cell differentiation, Salmonella, EBV and other pathogen infection (Fig
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