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Butyrate, in particular, inhibits HDAC3, reduces mTOR activation and glycolysis, enhances macrophage bactericidal activity, and promotes an anti-inflammatory phenotype (92)

During the past 30 years, there has been a renaissance of interest and an expanded view of the contributions of copper to brain function and pathophysiology, as reflected in follow-up statistics, and throughout the literature [18, 42, 63, 69, 235,236,237,238,239,240,241,242,243,244,245,246,247,248] (Fig

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