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Studies showing meaningful effects generally used 1,000mg or more per day

The decreased expression and signaling of TLRs, essential for recognizing pathogen-associated molecular patterns (PAMPs), further impair the ability of aging macrophages to phagocyte apoptotic cells and respond to pathogens

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These reactions tend to be mild, Connor says, but contact your healthcare provider if a more severe rash or hives develop, or theres swelling at the injection site