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Modulates expression of over 4,000 genes involved in tissue remodeling, including upregulation of collagen, elastin, and glycosaminoglycan synthesis

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the FDA has stated it lacks sufficient information to know whether the substance would cause harm when administered to humans Evidence snapshot: The evidence base is almost entirely preclinical, decades of animal (largely rat) studies, mostly from one Croatian research group (Sikiric et al., University of Zagreb), with a single small human trial under the brand name "Bepecin" (around 2015) that did not lead to any FDA-approved use

Storage Refrigerate after reconstitution

Transwell migration assay L929 cells (1 10 5 cells per well) were seeded into the upper chamber (8 m pore size)

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