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Host-microbe-drug-Nutrient screen identifies bacterial effectors of metformin therapy

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TRANSCEND-T2D-1 (NCT06354660), the program's first trial, reported topline results March 19, 2026, with full publication in The Lancet in June

FDA-approved uses Zepbound is FDA-approved for chronic weight management in patients with: Obesity (body mass index of 30 kg/m or higher) or Overweight (BMI of 27 or higher) with at least one health problem caused or worsened by being overweight