can you lose weight on glp 1 without dieting GLP-1 Loss Calorie Deficit GLP-1? No. 🚫💉 No medications

rskov C, Holst JJ, Knuhtsen S, Baldissera FGA, Plulsen Ss, Nielsen OV

Fermentation of fiber by gut bacteria also produces short-chain fatty acids that directly stimulate L-cells

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The trial met its primary endpoint, demonstrating that semaglutide 7.2 mg led to significantly greater weight loss at week 72 compared to placebo

FDA labeling notes postmarketing reports of acute kidney injury in patients treated with semaglutide, the majority in people who had gastrointestinal reactions leading to dehydration, and it instructs patients to promptly report persistent nausea, vomiting, or diarrhea to their healthcare provider

Administration of bumetanide, an NKCC1 chloride importer antagonist, can restore the GABA developmental shifts eliminated by Mecp2 mutations and reduce the increased glutamatergic/GABAergic PSC ratio (77)