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Description

While no effect of water volume with dosing on SNAC pharmacokinetics was observed, interestingly, SNAC exposure increased when shortening the post-dose fasting period from 120 to 30 min in the dosing conditions trial (Supplementary Fig

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More serious adverse events, such as gastrointestinal perforation (0.3%), esophageal mucosal injury (0.8%), gastric ulcer/bleeding (0.76%), and gastric outlet/bowel obstruction (0.12%), are relatively rare

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