A new Veterans Affairs study published in JAMA Network Open found that GLP-1 users had a higher three-year risk of non-arteritic anterior ischemic optic neuropathy than patients using older SGLT2 diabetes medications
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Semaglutide Semaglutide is a modified GLP-1 analog engineered with an albumin-binding fatty acid side chain that extends its half-life in research models
doi:10.12688/f1000research.12120.1 Belenky P, Bogan KL, Brenner C
As a GLP-1 receptor agonist, common side effects may include gastrointestinal issues
After 1-year follow-up, the mean reduction in A1C was significantly greater in the biphasic (1.3%) and prandial groups (1.4%) than in the basal group (0.8%).[144] However, after 3 years, basal or prandial insulin-based regimen had better A1C control than biphasic insulin-based regimen.[145] Safety tolerability and body weight The combination of insulin and SU results in a reduction of necessary insulin dose per day.[60,138] However, most studies adding SUs to insulin reported milder hypoglycemic episodes versus insulin monotherapy (range: 2.26.1 vs
