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OXM exerts its homeostatic effects on energy balance by increasing energy expenditure via the glucagon receptor and decreasing energy intake, likely through hypothalamic and area postrema activation by GLP-1R signaling 207,211

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11 A recent phase 2 clinical trial of tetrathiomolybdate showed a significant reduction in free copper in people with Wilson disease treated with tetrathiomolybdate, with no cases of paradoxical neurologic worsening

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Rabi FA, Al Zoubi MS, Kasasbeh GA, Salameh DM

Understanding GLP-1 Medications and their Benefits GLP-1 receptor agonists are commonly used to treat type 2 diabetes and obesity