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Focus on lean protein at every meal (aim for 60 to 100 grams per day), stay hydrated with at least 64 ounces of water daily, eat smaller meals more frequently, and avoid high-fat, fried, and overly sugary foods that can worsen nausea and GI side effects

Collaborative care between primary care providers and endocrinology specialists often provides optimal management for patients with both Hashimoto's thyroiditis and metabolic conditions requiring tirzepatide therapy

However, the results should not be interpreted as evidence that these medications prevent dementia, progressive cognitive decline, or psychiatric disease, because the study relied on diagnosis codes and remains vulnerable to residual confounding and misclassification

Studies consistently show that people who combine tirzepatide with structured resistance training preserve significantly more muscle than those who rely on the medication alone