Key ones include: Magnesium citrate (200-400 mg daily): Helps prevent constipation, supports sleep quality, and reduces muscle cramps B12 or methylcobalamin: GLP-1 agonists can reduce B12 absorption over time, and some compounded formulations include B12 in the compound for this reason Electrolytes: Sodium, potassium, and magnesium supplementation helps offset the dehydration risk from reduced food intake Protein powder: A practical way to maintain protein targets when appetite makes eating full meals difficult Some compounded formulations include additional ingredients like glycine , niacinamide , or glycine plus B12 combinations
Over five years, non-GLP-1 spending increases by $6,800, or 30 percent of the amount spent on GLP-1s
Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review" (2026)
Sources: David Jockers, DC
Plan for follow-up pricing from month two
When those prove insufficient, doctors layer on additional medications
