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Detoxification: Glutathione is the bodys premier detoxifying agent
The pharmacological properties of APAP are the focus of some activity, with the role of the metabolite N -arachidonoylaminophenol (AM404) still a topic of debate
If its not followed correctly, side effects can be tricky
Water stress induces up-regulation of DOF1 and MIF1 transcription factors and downregulation of proteins involved in secondary metabolism in amaranth roots ( Amaranthus hypochondriacus L.)
Abbreviations GSH glutathione SH sulfhydryl group O 2 superoxide H 2 O 2 hydrogen peroxide NOX NADPH oxidase SOD superoxide dismutase HOCl hypochlorous acid HOBr hypobromous acid Fe 2+ ferrous iron OH hydroxyl radical Fe 3+ ferric iron L lipid radical LOO hydroperoxide radical LOOH lipid peroxide HNE 4-hydroxy-2-nonenal ONOO peroxynitrite NO nitrogen oxide nitrite nitrate ONOOH peroxynitrous acid NO 2 nitrogen dioxide CFTR cystic fibrosis transport receptor GPx glutathione peroxidase PHGPx GPx IV phospholipid hydroperoxide glutathione peroxidase GSSG glutathione disulfide Prdx peroxiredoxin PSSG protein mixed disulfide PDI protein disulfide isomerase S thiolate PSOH sulfenic acid GST glutathione-S transferase GSNO nitrosoglutathione DTNB dithionitrobenzoic acid NEM N-ethylmaleimide NaBH 4 sodium borohydride OPT orthophthaldehyde GCL glutamate cysteine ligase ARE antioxidant response element JNK Jun N-terminal kinase GGT -glutamyl transpeptidase
