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Since weight reduction was our primary analyses involved the use of the BMI-based model as described above, and given that weight reduction was the primary endpoint in the SURMOUNT-1 trial, a sensitivity analysis was done using the laboratory-based equations [13] (Appendix) and the respective SURMOUNT-1 trial effects on total and high-density lipoprotein-cholesterol (HDL-C) (of 7.4% and + 8.2%, respectively) instead of BMI
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