semaglutide and cardiovascular outcomes in obesity without diabetes journal club 🚨 Oral 25 mg delivers double-digit weight loss OASIS-4 (Phase 3 trial) - Weight loss and cardiovascular disease

May 12, 2011. Public Advisory

H.EdwardsN.RapoportR.WisemanE.et al (2000)

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The medication activates GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors

However, the precise mechanisms linking gut microbiota, GLP-1 secretion, and host metabolic regulation remain incompletely understood and warrant further investigation

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