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Furthermore, berberine is believed to stimulate GLP-1 secretion by activating bitter taste receptors (TAS2Rs) and associated phospholipase C (PLC)-dependent pathways within intestinal L cells (Y Yu et al., 2015)

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Children 10%): Nausea, hypoglycemia (when used with sulfonylureas/insulin), vomiting, diarrhea, abdominal pain, constipation, dyspepsia, flatulence

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Hold the pen steady for three seconds after needle insertion to ensure the full dose enters subcutaneous tissue rather than remaining in the dermis