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The compounding effect of sustained caloric reduction produces significant body composition changes

They are rarely a cause for concern

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But there is a parallel conversation building in the longevity and geroscience literature that, if it pans out the way its early signals suggest, will eventually swallow the obesity framing entirely

To remove the nuclei and cell debris, the homogenate was first centrifuged at a low speed at 700 g for 8 min (2)