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Iron overload increases ferritin levels and decreases RUNX2 levels in BMSCs, causing irregular morphological changes, significantly reducing their activity, and inhibiting osteogenic differentiation, while melatonin therapy could reverse this process and promote osteogenic differentiation of BMSCs

Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1

Yang XD et al

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By reducing pigmentation, it helps the skin achieve a lighter and brighter appearance