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If you experience any of these two adverse effects, contact your doctor

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Cells were first gently lysed with the cytoplasmic extraction buffer to release cytoplasmic components, and the supernatant was collected after centrifugation as the cytoplasmic protein fraction

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Moreover, GERD amelioration might require 10% BW loss, which is hardly achievable and sustainable without pharmacotherapy 108

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Acknowledgements The authors are grateful to the Department of Pharmacy, School of Healthcare & Allied Sciences, GD Goenka University, Gurugram and School of Pharmacy, Krishna Institute of Engineering and Technology, Ghaziabad for providing the necessary facilities

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Future research should focus on further optimisation of these analogues, exploring formulation strategies that maximise absorption and therapeutic effectiveness

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