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liraglutide at low doses alone, did not demonstrate the greater efficacy of the combination therapy, as the area of VAT was reduced in all the three treatments arms without inter-groups differences [59, 60]

The 1298C is important in the conversion of BH2 to BH4, which plays a huge role in mood regulation and addictive behavior (34)

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All participants had a diagnosis of ASD established with DSM-IV-TR or DSM-5 and validated with ADOS-2 and/or ADI-R, while individuals with neurological or psychiatric comorbidities, recent probiotic or oxytocin use, or unstable medications were excluded

However, diversity in trial designs, constrained sample numbers, and short follow-up durations limit the capacity to reach conclusive determinations

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