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Others remain emerging or indirect

GLP-1 receptor agonists may be appropriate second-line agents after metformin or even first-line in patients with established cardiovascular disease, chronic kidney disease, or when weight management is a priority

Genetic instruments for GLP-1RAs were obtained from the cis-expression quantitative trait loci of the GLP1R gene, on the basis of data from the eQTLGen Consortium

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