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In vitro studies often include compound stability analysis, redox response evaluation, and comparative testing under varied laboratory conditions

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As this excess persists, the storage capacity of adipose tissue is exceeded, leading to oxidative stress and immune cell infiltration (17)

Mechanistically, USP7-mediated deubiquitination of H2BK120ub facilitates PRMT6-dependent deposition of the repressive mark H3R2me2a, concomitant with the exclusion of activating H3K4me3

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