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Echinocandin resistance is primarily driven by mutations in FKS1 , while drug-induced cell wall stress can activate tolerance pathways such as the Ca + /calcineurin and Hsp90/mTOR signaling cascades (Perlin, 2007

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Its half-life is 4 days in human erythrocytes, 2 to 4 h in the cytosol of rat hepatic cells and 30 h in the mitochondrial lumen [43]

Este efecto normalizador pineal se entiende que est por encima de muchas de sus otras acciones biolgicas

Plant Physiol 176(1):930945

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