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Biopsy results are less than ideal, however, as the procedure samples only a very small amount of liver tissue and the biopsy material may not represent the most severe changes in the liver

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If more than 5 days have passed, skip the missed dose and take the next dose on the next scheduled day according to your dosing schedule

If switching is not possible or not preferred, a pragmatic approach involves increasing oral progesterone from 100 mg to 200 mg daily for the first 4-6 weeks of semaglutide treatment

doi: 10.1006/cyto.1999.0661 219 ConnorTJStarrNOSullivanJBHarkinA