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Knockout of either Grx5 or Grx3 leads to iron accumulation in cells [31,136,137] , impaired FeS cluster biosynthesis [138] , and deregulated iron homeostasis via IRPs [31,137,139] (Figure 4)
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788 Unlike CD8 + T cells, Tregs increase fatty acid utilization through CD36, aiding their function and adaptation in the TME and thereby maintaining survival and immunosuppressive capacities
Indirectly, yes
Immunogenic cell death in hematological malignancy therapy
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