GLP-1 receptor activation in research models consistently associates with reduced appetite signaling and enhanced insulin secretion
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Activation of gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis
The R code used to generate the results is available in the github repository Results Antagonism of NMDA Receptors Leads to Increased Release of GLP-1 From GLUTag Cells The addition of the non-competitive NMDA receptor antagonist MK-801 (10 M) for 2 h to GLUTag cells cultured in buffer containing glycine with glutamate showed a 37% increase in GLP-1 release relative to control samples (Figure 1A, open diamonds, 1,045 142 pg GLP-1/ml vs
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