Only if the diet rebuilds SCFA-producing microbes, mucosal structure, and circadian metabolic alignment
The differences between groups were small enough that they could easily have happened by chance
For constipation management, increasing soluble fibre gradually (such as ispaghula/psyllium) is recommended by NICE guidance for IBS, while excessive insoluble fibre should generally be avoided as it may worsen symptoms
Disclosure: Im a paid contributor to NutritionNC.com and was not compensated by IVIM for this review
This can be appropriate but requires careful evaluation
However, several factors could accelerate a reversal: declining GLP-1 drug prices through manufacturer competition or government negotiation, improved adherence data from newer formulations, long-term outcomes studies demonstrating cardiovascular benefit that changes the cost-benefit analysis, and state legislative mandates requiring obesity treatment coverage