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Cell Mol Gastroenterol Hepatol

The STEP 5 data suggests that ongoing administration is necessary to maintain results, as participants who discontinued semaglutide in the STEP 1 extension study regained approximately two-thirds of the weight they had lost within one year of stopping

Very few drugs pay for themselves, and it's a bit unfair and I think premature to evaluate GLP-1's effectiveness or cost-effectiveness, or even whether it offsets spending based on the criteria, just because we've seen that it treats so many things so well

The medical standards at reputable Bangkok clinics are equivalent, making Thailand a popular destination for wellness travel

In other words, GLP-1 medications dont reverse lymphedema, although they can potentially help decrease swelling

Discuss with your provider whether long-term low-dose therapy or complete discontinuation better suits your goals and risk of regain