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Ideally, youd want labs done at the beginning and again with each dose increase, or at least every 36 months, to make sure the medication is working safely and not causing unwanted side effects

Constipation: Semaglutide can sometimes cause difficulty in passing stools, leading to constipation

Glucose metabolism in cardiac hypertrophy and heart failure

In Phase 2 trials, participants achieved an average weight loss of 24.2% of their body weight over 48 weeks

For example, liraglutide was associated with a non-significant increased risk of HF relative to placebo [odds ratio ( OR ) = 4.85, 95% CI 0.7531.36] [89]