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Common adrenal hormone disorders include adrenal insufficiency, Cushings syndrome, and adrenal tumors ( 3.1 Adrenal insufficiency When the adrenal glands do not produce enough cortisol and, occasionally, aldosterone, it is known as adrenal insufficiency ( 3.2 Cushings syndrome Long-term cortisol exposure causes Cushings syndrome

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A previous study focusing on the acute cardioprotective effects of exendin-4 in a rat ischemia/reperfusion model demonstrated that PI3K/AKT signaling pathway activation exerted cardioprotective effects attributable to its pro-survival and antiapoptotic effects (12)

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